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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

therapeutic equivalency

,

,

,

cardiovascular diseases

,

diabetes mellitus

,

ciliary motility disorders

,

sickle cell anemia

,

,

major depressive disorder

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

lambert-eaton myasthenic syndrome

,

congenital myasthenic syndromes

,

newborn respiratory distress syndrome

,

,

pulmonary hypertension

,

discoid lupus erythematosus

,

systemic lupus erythematosus

,

,

lymphangioleiomyomatosis

,

viral bronchiolitis

,

,

pulmonary edema

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

altitude sickness

,

post-acute covid-19 syndrome

,

cystic fibrosis

,

respiratory distress syndrome

,

,

,

respiratory tract diseases

,

respiration disorders

,

acute lung injury

,

bronchial hyperreactivity

,

transient tachypnea of the newborn

,

retinopathy of prematurity

,

wounds and injuries

,

,

vascular diseases

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

retinal diseases

,

premature birth

,

myasthenia gravis

,

familial dysautonomia

,

critical illness

,

organophosphate poisoning

,

,

exercise-induced allergies

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

respiratory aspiration

,

healthy volunteers/patients

,

,

status asthmaticus

,

bronchial spasm

,

exercise-induced asthma

,

hypersensitivity

,

,

respiratory sounds

,

disease progression

,

,

,

,

,

respiratory insufficiency

,

,

allergic rhinitis

,

airway obstruction

,

chronic bronchitis

,

bronchoconstriction

,

bronchiolitis obliterans

,

,

chronic disease

,

,

respiratory tract infections

,

pulmonary eosinophilia

,

,

,

bronchiolitis obliterans syndrome

,

respiratory hypersensitivity

,

,

insulin resistance

,

pediatric obesity

,

pulmonary emphysema

,

spinal cord injuries

,

glycogen storage disease type ii

,

,

allergic rhinitis seasonal

,

,

muscle weakness

,

drug-related side effects and adverse reactions

,

,

,

bronchopulmonary dysplasia

,

mucociliary clearance

,

bronchial diseases

,

mechanical ventilators

,

,

depressive disorder

,

metabolic bone diseases

,

,

heart septal defects

,

ventricular heart septal defects

,

,

,

,

,

pharmacokinetics

,

,

cesarean section

,

,

water-electrolyte imbalance

,

immune system diseases

,

,

airway remodeling

,

,

respiratory signs and symptoms

,

,

muscular dystrophies

,

child mortality

,

noninvasive ventilation

,

artificial respiration

,

pulmonary atelectasis

,

acute kidney injury

,

vitamin d deficiency

,

medication adherence

,

tobacco use disorder

,

tobacco smoking

,

sleep wake disorders

,

obstructive sleep apnea

,

,

food hypersensitivity

,

mitochondrial diseases

,

,

alpha 1-antitrypsin deficiency

,

argininosuccinic aciduria

,

substance-related disorders

,

,

renal insufficiency

,

essential hypertension

,

aortic valve stenosis

,

,

,

,

,

,

pathologic dilatation

,

,

asthma-chronic obstructive pulmonary disease overlap syndrome

,

,

heart-lung transplantation

,

oxygen consumption

,

,

extrinsic allergic alveolitis

,

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

lactic acidosis

,

cardiomyopathies

,

hematopoietic stem cell transplantation

,

atrial fibrillation

,

,

dust mite allergy

,

,

pulmonary tuberculosis

,

chronic kidney failure

,

multiple sclerosis

,

autoimmune diseases

,

facioscapulohumeral muscular dystrophy

,

,

,

,

,

nemaline myopathies

,

muscular diseases

,

musculoskeletal diseases

,

neuromuscular diseases

,

myotonia congenita

,

structural myopathies congenital

,

communicable diseases

,

autonomic nervous system diseases

,

liver transplantation

,

non-small-cell lung carcinoma

,

human influenza

,

one-lung ventilation

,

,

immunologic deficiency syndromes

,

primary immunodeficiency diseases

,

,

,

,

metabolic syndrome

,

rheumatoid arthritis

chronic obstructive pulmonary disease

,

obstructive lung diseases

Tiotropium bromide anhydrous

chronic obstructive pulmonary disease

,

obstructive lung diseases

Mexiletine hydrochloride

,

,

peripheral nervous system diseases

,

acquired immunodeficiency syndrome

,

communicable diseases

,

nervous system diseases

Bupropion hydrochloride

healthy volunteers/patients

,

,

depressive disorder

,

tobacco use disorder

,

,

,

type 2 diabetes mellitus

,

diabetes mellitus

,

,

cardiovascular diseases

breast neoplasms

acquired immunodeficiency syndrome

,

aids-related complex

,

,

,

neuromyelitis optica

,

hematologic diseases

,

immunoproliferative disorders

,

transitional cell carcinoma

,

b-cell leukemia

,

,

transverse myelitis

,

psoriatic arthritis

,

bites and stings

,

pathologic processes

,

,

diffuse intrinsic pontine glioma

,

infectious pregnancy complications

,

renal insufficiency

,

thyroid neoplasms

,

parotid neoplasms

,

neovascular glaucoma

,

intraocular lymphoma

,

eosinophilic esophagitis

,

,

hiv seronegativity

,

hereditary hemorrhagic telangiectasia

,

,

,

open-angle glaucoma

,

,

,

,

communicable diseases

,

,

,

hemangioblastoma

,

von hippel-lindau disease

,

acute lung injury

,

newborn respiratory distress syndrome

,

ischemic stroke

,

cerebral infarction

,

brain neoplasms

,

,

,

,

large b-cell lymphoma diffuse

,

,

stomach neoplasms

,

esophageal neoplasms

,

,

prostatic neoplasms

,

,

hypersensitivity

,

,

endometrial neoplasms

,

head and neck neoplasms

,

multiple myeloma

,

kidney neoplasms

,

urinary bladder neoplasms

,

retinal diseases

,

hodgkin disease

,

peritoneal neoplasms

,

uterine cervical neoplasms

,

salivary gland neoplasms

,

biliary tract neoplasms

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

,

hemangiosarcoma

,

polypoidal choroidal vasculopathy

,

b-cell lymphoma marginal zone

,

,

central nervous system neoplasms

,

plasma cell neoplasms

,

basal cell carcinoma

,

,

malignant fibrous histiocytoma

,

,

relapsing-remitting multiple sclerosis

,

meningeal neoplasms

,

meningeal carcinomatosis

,

animal mammary neoplasms

,

lymphoproliferative disorders

,

lymphatic diseases

,

hematologic neoplasms

,

,

focal segmental glomerulosclerosis

,

respiratory distress syndrome

,

,

cutaneous malignant melanoma

,

squamous cell carcinoma of head and neck

,

mantle-cell lymphoma

,

waldenstrom macroglobulinemia

,

,

,

oligodendroglioma

,

unknown primary neoplasms

,

cholangiocarcinoma

,

radiation injuries

,

diabetic retinopathy

,

,

basal cell neoplasms

,

,

benign fibrous histiocytoma

,

local neoplasm recurrence

,

left ventricular dysfunction

,

reactive arthritis

,

urologic neoplasms

,

osteitis deformans

,

congenital heart defects

,

protein-losing enteropathies

,

immunoglobulin light-chain amyloidosis

,

,

male breast neoplasms

,

medulloblastoma

,

primitive neuroectodermal tumors

,

infratentorial neoplasms

,

retinal degeneration

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

myeloid leukemia acute

,

,

respiratory insufficiency

,

severe acute respiratory syndrome

,

,

neurofibrosarcoma

,

gastrointestinal stromal tumors

,

kidney diseases

,

,

interstitial nephritis

,

adrenocortical carcinoma

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

burkitt lymphoma

,

large-cell lymphoma immunoblastic

,

churg-strauss syndrome

,

bronchiolitis obliterans syndrome

,

,

,

digestive system neoplasms

,

,

,

thymus neoplasms

,

precancerous conditions

,

monoclonal gammopathy of undetermined significance

,

neurofibromatosis 2

,

acoustic neuroma

,

peripheral nervous system diseases

,

myasthenia gravis

,

,

vaginal neoplasms

,

vulvar neoplasms

,

gallbladder neoplasms

,

basal cell nevus syndrome

,

tongue neoplasms

,

,

dermatomyositis

,

,

pseudotumor cerebri

,

,

orbital pseudotumor

,

lymphadenopathy

,

,

autoimmune pancreatitis

,

retroperitoneal fibrosis

,

antiphospholipid syndrome

,

uterine neoplasms

,

central nervous system diseases

,

,

st elevation myocardial infarction

,

inferior wall myocardial infarction

,

,

synovial sarcoma

,

myxoid liposarcoma

,

hereditary sensory and autonomic neuropathies

,

,

,

orbital diseases

,

,

ocular motility disorders

,

,

opsoclonus-myoclonus syndrome

,

neuroendocrine carcinoma

,

hairy cell leukemia

,

spinocerebellar degenerations

,

chronic obstructive pulmonary disease

,

,

breast neoplasms

,

non-small-cell lung carcinoma

,

,

,

non-hodgkin lymphoma

,

,

neoplasm metastasis

,

ovarian neoplasms

,

b-cell chronic lymphocytic leukemia

,

fallopian tube neoplasms

,

b-cell lymphoma

,

rheumatoid arthritis

,

renal cell carcinoma

,

pancreatic neoplasms

,

,

lymphoid leukemia

,

colonic neoplasms

,

rectal neoplasms

,

,

follicular lymphoma

,

ovarian epithelial carcinoma

,

,

triple negative breast neoplasms

,

chronic urticaria

,

,

diabetes mellitus

,

,

peanut hypersensitivity

,

,

multiple sclerosis

,

thrombocytopenic purpura idiopathic

,

thrombocytopenic purpura

,

,

kidney transplantation

,

neuroendocrine tumors

,

lupus nephritis

,

vision disorders

,

systemic lupus erythematosus

,

hypopituitarism

,

cystic fibrosis

,

central venous catheters

,

venous thrombosis

,

postthrombotic syndrome

,

thrombotic thrombocytopenic purpura

,

,

carcinoid tumor

,

,

paraneoplastic syndromes

,

islet cell carcinoma

,

islet cell adenoma

,

,

,

somatostatinoma

,

,

chronic progressive multiple sclerosis

,

venous thromboembolism

,

postphlebitic syndrome

,

nephrotic syndrome

,

,

diffuse cerebral sclerosis of schilder

,

interstitial lung diseases

,

pleural effusion

,

,

colorectal neoplasms

,

macular degeneration

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

choroidal neovascularization

,

retinal vein occlusion

,

healthy volunteers/patients

,

pituitary dwarfism

,

granulomatosis with polyangiitis

,

microscopic polyangiitis

,

,

,

,

chronic kidney failure

,

,

,

myocardial infarction

,

,

,

,

primary ovarian insufficiency

,

,

turner syndrome

,

gonadal dysgenesis

,

premature menopause

,

chronic renal insufficiency

,

failure to thrive

,

pulmonary embolism

,

,

iga glomerulonephritis

,

bullous pemphigoid

,

retinal neovascularization

,

growth disorders

,

sickle cell anemia

,

atopic dermatitis

,

,

kaposi varicelliform eruption

,

,

,

,

chronic obstructive pulmonary disease

,

respiratory aspiration

,

healthy volunteers/patients

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

triple negative breast neoplasms

,

kidney neoplasms

,

b-cell lymphoma

,

fallopian tube neoplasms

,

follicular lymphoma

,

pancreatic neoplasms

,

endometrial neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

gastrointestinal neoplasms

,

,

urinary bladder neoplasms

,

uterine cervical neoplasms

,

biliary tract neoplasms

,

gallbladder neoplasms

,

,

,

hepatocellular carcinoma

,

liver neoplasms

,

prostatic neoplasms

,

non-small-cell lung carcinoma

,

,

colorectal neoplasms

,

renal cell carcinoma

,

breast neoplasms

,

non-hodgkin lymphoma

,

,

,

essential hypertension

,

castration-resistant prostatic neoplasms

,

gastrointestinal stromal tumors

,

,

,

,

,

neoplasm metastasis

,

erectile dysfunction

,

large b-cell lymphoma diffuse

,

macular degeneration

,

,

hookworm infections

,

,

ancylostomiasis

,

ischemic stroke

,

,

cerebrovascular disorders

,

transient ischemic attack

,

thromboembolism

,

,

,

,

,

acute coronary syndrome

,

,

venous thromboembolism

,

atrial fibrillation

,

,

,

,

,

healthcare-associated pneumonia

,

bacterial pneumonia

,

community-acquired pneumonia

,

thyroid neoplasms

,

thyroid diseases

,

retinal diseases

,

wet macular degeneration

,

retinal degeneration

,

,

,

Globulin, immune

rectal neoplasms

,

ovarian epithelial carcinoma

,

b-cell lymphoma marginal zone

,

colonic neoplasms

,

intestinal neoplasms

,

hematologic diseases

,

myeloid leukemia

,

myelomonocytic leukemia juvenile

,

,

laryngeal diseases

,

,

liver neoplasms

,

alveolar soft part sarcoma

,

,

healthy volunteers/patients

,

,

,

,

esophageal neoplasms

,

,

,

clear cell adenocarcinoma

,

,

thymus neoplasms

,

,

central nervous system neoplasms

,

biphenotypic leukemia acute

,

burkitt lymphoma

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

digestive system diseases

,

colonic diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

colorectal neoplasms

,

renal cell carcinoma

,

triple negative breast neoplasms

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

,

alzheimer disease

,

kidney neoplasms

,

b-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

large b-cell lymphoma diffuse

,

prostatic neoplasms

,

multiple sclerosis

,

squamous cell carcinoma

,

,

pancreatic neoplasms

,

ovarian neoplasms

,

,

myelodysplastic syndromes

,

myeloid leukemia acute

,

sickle cell anemia

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

castration-resistant prostatic neoplasms

,

intestinal diseases

,

mantle-cell lymphoma

,

,

,

myelomonocytic leukemia chronic

,

bone marrow diseases

,

hypercholesterolemia

,

atherosclerosis

,

hepatocellular carcinoma

,

allergic rhinitis

,

,

,

invasive hydatidiform mole

,

stomach neoplasms

,

streptococcal infections

,

inflammatory bowel diseases

,

human influenza

,

,

waldenstrom macroglobulinemia

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

margins of excision

,

hereditary sensory and autonomic neuropathies

,

,

cardiovascular diseases

,

type 2 diabetes mellitus

,

hyperlipoproteinemia type ii

,

,

pancreatic ductal carcinoma

,

membranous glomerulonephritis

,

,

small cell lung carcinoma

,

neuroendocrine tumors

,

mucocutaneous lymph node syndrome

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

hidradenitis suppurativa

,

,

anaplastic thyroid carcinoma

,

communicable diseases

,

bacterial infections

,

gram-positive bacterial infections

,

,

smoldering multiple myeloma

,

second primary neoplasms

,

,

japanese encephalitis

,

,

central serous chorioretinopathy

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

squamous cell neoplasms

,

hodgkin disease

,

neuroendocrine carcinoma

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

fallopian tube neoplasms

,

coronavirus infections

,

,

,

eosinophilic esophagitis

,

,

female infertility

,

solar urticaria

,

angioid streaks

,

pseudoxanthoma elasticum

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

diffuse scleroderma

,

hemolytic anemia autoimmune

,

,

,

non-small-cell lung carcinoma

,

,

,

,

meningococcal meningitis

,

iga glomerulonephritis

,

cryopyrin-associated periodic syndromes

,

,

b-cell chronic lymphocytic leukemia

,

non-hodgkin lymphoma

,

,

,

,

follicular lymphoma

,

brain neoplasms

,

lymphoid leukemia

,

paroxysmal hemoglobinuria

,

retinopathy of prematurity

,

,

graft rejection

,

aplastic anemia

,

,

,

,

glomerulonephritis

,

juvenile arthritis

,

haemophilus infections

,

degenerative myopia

,

ankylosing spondylitis

,

polymyalgia rheumatica

,

graft vs host disease

,

psychology rejection

,

organ transplantation

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

gouty arthritis

,

osteitis deformans

,

,

allergic rhinitis seasonal

,

,

peanut hypersensitivity

,

hematologic neoplasms

,

,

neovascular glaucoma

,

giant cell arteritis

,

,

,

neoplasms by site

,

thrombocytopenic purpura idiopathic

,

chronic obstructive pulmonary disease

,

urologic diseases

,

,

,

,

familial mediterranean fever

,

,

axial spondyloarthritis

,

,

,

,

,

,

,

thrombotic microangiopathies

,

atypical hemolytic uremic syndrome

,

choroid diseases

,

uveal neoplasms

,

,

,

pulmonary eosinophilia

,

,

,

alpha 1-antitrypsin deficiency

,

lupus nephritis

,

immune system diseases

,

autoimmune diseases

,

male urogenital diseases

,

,

female urogenital diseases

,

female urogenital diseases and pregnancy complications

,

urogenital diseases

,

lymphoproliferative disorders

,

neoplasms by histologic type

,

,

breast neoplasms

,

macular degeneration

,

,

,

,

,

choroidal neovascularization

,

vision disorders

,

kidney transplantation

,

meningococcal infections

,

retinal vein occlusion

,

neoplasm metastasis

,

rheumatoid arthritis

,

chronic urticaria

,

psoriatic arthritis

,

diabetic retinopathy

,

,

liver transplantation

,

relapsing-remitting multiple sclerosis

,

kidney diseases

,

diabetes mellitus

,

spondylarthritis

,

retinal diseases

,

chronic renal insufficiency

,

,

wet macular degeneration

,

geographic atrophy

,

pathologic neovascularization

,

,

polypoidal choroidal vasculopathy

,

hypersensitivity

,

renal insufficiency

,

chronic kidney failure

,

,

retinal neovascularization

,

retinal detachment

,

diabetes complications

,

thrombocytopenia

,

migraine disorders

,

,

,

,

food hypersensitivity

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

tick-borne encephalitis

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

,

liver cirrhosis

,

,

,

reperfusion injury

,

delayed graft function

,

hemoglobin sc disease

,

vaso-occlusive crises

,

,

,

hematopoietic stem cell transplantation

,

chronic progressive multiple sclerosis

Butylscopolamine bromide

obstructive lung diseases

,

,

chronic obstructive pulmonary disease

,

1

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