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Status:

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Phases:

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Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

tobacco use disorder

,

cigarette smoking

,

smoking cessation

,

alzheimer disease

,

,

psychomotor agitation

,

treatment-resistant depressive disorder

,

,

major depressive disorder

,

depressive disorder

,

therapeutic equivalency

,

,

,

cardiovascular diseases

,

diabetes mellitus

,

ciliary motility disorders

,

sickle cell anemia

,

major depressive disorder

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

lambert-eaton myasthenic syndrome

,

congenital myasthenic syndromes

,

newborn respiratory distress syndrome

,

,

pulmonary hypertension

,

discoid lupus erythematosus

,

systemic lupus erythematosus

,

,

lymphangioleiomyomatosis

,

viral bronchiolitis

,

,

pulmonary edema

,

amyotrophic lateral sclerosis

,

motor neuron disease

,

altitude sickness

,

post-acute covid-19 syndrome

,

cystic fibrosis

,

respiratory distress syndrome

,

,

,

respiratory tract diseases

,

respiration disorders

,

acute lung injury

,

bronchial hyperreactivity

,

transient tachypnea of the newborn

,

,

retinopathy of prematurity

,

wounds and injuries

,

,

vascular diseases

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

retinal diseases

,

premature birth

,

myasthenia gravis

,

familial dysautonomia

,

critical illness

,

organophosphate poisoning

,

,

exercise-induced allergies

,

,

,

chronic obstructive pulmonary disease

,

obstructive lung diseases

,

,

respiratory aspiration

,

healthy volunteers/patients

,

,

status asthmaticus

,

bronchial spasm

,

exercise-induced asthma

,

hypersensitivity

,

,

respiratory sounds

,

disease progression

,

,

,

respiratory insufficiency

,

,

,

,

allergic rhinitis

,

airway obstruction

,

chronic bronchitis

,

bronchoconstriction

,

bronchiolitis obliterans

,

,

chronic disease

,

,

respiratory tract infections

,

pulmonary eosinophilia

,

,

,

bronchiolitis obliterans syndrome

,

respiratory hypersensitivity

,

,

pediatric obesity

,

pulmonary emphysema

,

spinal cord injuries

,

glycogen storage disease type ii

,

,

insulin resistance

,

allergic rhinitis seasonal

,

,

muscle weakness

,

drug-related side effects and adverse reactions

,

,

,

bronchopulmonary dysplasia

,

mucociliary clearance

,

bronchial diseases

,

mechanical ventilators

,

,

depressive disorder

,

metabolic bone diseases

,

,

heart septal defects

,

ventricular heart septal defects

,

,

,

,

,

pharmacokinetics

,

,

cesarean section

,

,

water-electrolyte imbalance

,

immune system diseases

,

,

airway remodeling

,

,

respiratory signs and symptoms

,

,

muscular dystrophies

,

child mortality

,

noninvasive ventilation

,

artificial respiration

,

pulmonary atelectasis

,

acute kidney injury

,

vitamin d deficiency

,

medication adherence

,

tobacco use disorder

,

tobacco smoking

,

sleep wake disorders

,

obstructive sleep apnea

,

,

food hypersensitivity

,

mitochondrial diseases

,

,

alpha 1-antitrypsin deficiency

,

argininosuccinic aciduria

,

substance-related disorders

,

,

renal insufficiency

,

essential hypertension

,

aortic valve stenosis

,

,

,

,

,

,

pathologic dilatation

,

,

asthma-chronic obstructive pulmonary disease overlap syndrome

,

,

heart-lung transplantation

,

oxygen consumption

,

,

extrinsic allergic alveolitis

,

,

diaphragmatic hernias congenital

,

diaphragmatic hernia

,

lactic acidosis

,

cardiomyopathies

,

hematopoietic stem cell transplantation

,

atrial fibrillation

,

,

dust mite allergy

,

,

pulmonary tuberculosis

,

chronic kidney failure

,

multiple sclerosis

,

autoimmune diseases

,

facioscapulohumeral muscular dystrophy

,

,

,

,

,

nemaline myopathies

,

muscular diseases

,

musculoskeletal diseases

,

neuromuscular diseases

,

myotonia congenita

,

structural myopathies congenital

,

communicable diseases

,

autonomic nervous system diseases

,

liver transplantation

,

non-small-cell lung carcinoma

,

human influenza

,

one-lung ventilation

,

,

immunologic deficiency syndromes

,

primary immunodeficiency diseases

,

,

,

,

metabolic syndrome

,

rheumatoid arthritis

chronic obstructive pulmonary disease

,

obstructive lung diseases

Tiotropium bromide anhydrous

chronic obstructive pulmonary disease

,

obstructive lung diseases

Mexiletine hydrochloride

,

,

peripheral nervous system diseases

,

acquired immunodeficiency syndrome

,

communicable diseases

,

nervous system diseases

Bupropion hydrochloride

tobacco use disorder

,

cigarette smoking

,

smoking cessation

,

alzheimer disease

,

,

psychomotor agitation

,

treatment-resistant depressive disorder

,

,

major depressive disorder

,

depressive disorder

,

,

major depressive disorder

,

depressive disorder

breast neoplasms

,

prostatic neoplasms

,

neuroendocrine carcinoma

,

hodgkin disease

,

,

,

acquired immunodeficiency syndrome

,

progressive multifocal leukoencephalopathy

healthy volunteers/patients

,

alzheimer disease

,

female genital neoplasms

,

,

chronic hepatitis b

,

,

major depressive disorder

,

depressive disorder

,

triple negative breast neoplasms

,

pancreatic neoplasms

,

,

coronary disease

,

coronary artery disease

,

myocardial ischemia

,

,

,

sickle cell anemia

,

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

parkinson disease

,

autistic disorder

,

autism spectrum disorder

,

pervasive child development disorders

,

chronic hepatitis

,

rectal neoplasms

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

,

nasopharyngeal carcinoma

,

nasopharyngeal neoplasms

,

stomach neoplasms

,

esophageal neoplasms

,

,

neoplasm metastasis

,

antiphospholipid syndrome

,

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

lupus nephritis

,

human influenza

,

breast neoplasms

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

non-hodgkin lymphoma

,

myeloid leukemia acute

,

multiple sclerosis

,

,

,

hepatocellular carcinoma

,

colonic neoplasms

,

thrombocytopenic purpura idiopathic

,

liver cirrhosis

,

neuromyelitis optica

,

membranous glomerulonephritis

,

chronic progressive multiple sclerosis

,

,

nephrotic syndrome

,

ovarian neoplasms

,

ovarian epithelial carcinoma

,

,

hemolytic anemia autoimmune

,

,

chronic hepatitis c

,

,

,

rheumatoid arthritis

,

,

,

juvenile arthritis

,

,

follicular lymphoma

,

,

,

myelodysplastic syndromes

,

,

,

acquired immunodeficiency syndrome

,

kidney transplantation

,

drug-related side effects and adverse reactions

,

heart disease risk factors

,

cognitive dysfunction

healthy volunteers/patients

,

,

central nervous system neoplasms

,

nephrotic syndrome

,

laryngeal diseases

,

chronic hepatitis

,

,

esophageal neoplasms

,

postmenopausal osteoporosis

,

,

irritable bowel syndrome

,

pathologic dilatation

,

germ cell and embryonal neoplasms

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

oligodendroglioma

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

hypertrophic pyloric stenosis

,

ganglioneuroblastoma

,

phenylketonurias

,

neuroendocrine tumors

,

b-cell lymphoma marginal zone

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

rectal diseases

,

gastrointestinal diseases

,

intestinal neoplasms

,

digestive system diseases

,

colonic diseases

,

intestinal diseases

,

autism spectrum disorder

,

drug hypersensitivity

,

renal cell carcinoma

,

,

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

b-cell lymphoma

,

squamous cell carcinoma

,

large b-cell lymphoma diffuse

,

pancreatic ductal carcinoma

,

,

,

uveal neoplasms

,

,

lymphoid leukemia

,

mantle-cell lymphoma

,

myocardial infarction

,

kidney neoplasms

,

hereditary sensory and autonomic neuropathies

,

myelodysplastic syndromes

,

endometrial neoplasms

,

bronchiolitis obliterans syndrome

,

hypersensitivity

,

philadelphia chromosome

,

,

squamous cell neoplasms

,

waldenstrom macroglobulinemia

,

myeloid leukemia acute

,

multiple myeloma

,

castration-resistant prostatic neoplasms

,

hypertrophic cardiomyopathy

,

acute coronary syndrome

,

myocardial ischemia

,

unstable angina

,

margins of excision

,

gouty arthritis

,

gastrointestinal stromal tumors

,

,

,

retinitis pigmentosa

,

,

,

,

,

coronary artery disease

,

,

portal hypertension

,

atopic dermatitis

,

,

,

,

peritoneal neoplasms

,

intestinal obstruction

,

invasive hydatidiform mole

,

central serous chorioretinopathy

,

,

epstein-barr virus infections

,

oropharyngeal neoplasms

,

hodgkin disease

,

type 1 diabetes mellitus

,

,

neurofibrosarcoma

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

netherton syndrome

,

,

eosinophilic esophagitis

,

,

systemic mastocytosis

,

mast-cell leukemia

,

,

,

female infertility

,

sickle cell anemia

,

streptococcus agalactiae

,

angioid streaks

,

pseudoxanthoma elasticum

,

granulomatosis with polyangiitis

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

microscopic polyangiitis

,

diffuse scleroderma

,

t-cell lymphoma

,

malignant mesothelioma

,

clear cell adenocarcinoma

,

,

adenomyoepithelioma

,

colorectal neoplasms

,

non-small-cell lung carcinoma

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

,

prostatic neoplasms

,

,

myeloid leukemia

,

triple negative breast neoplasms

,

,

follicular lymphoma

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

cardiovascular diseases

,

graft vs host disease

,

,

psoriatic arthritis

,

,

rheumatoid arthritis

,

meningococcal meningitis

,

meningococcal infections

,

hypercholesterolemia

,

rectal neoplasms

,

osteitis deformans

,

,

degenerative myopia

,

non-hodgkin lymphoma

,

stomach neoplasms

,

,

neoplasms by site

,

inferior wall myocardial infarction

,

,

psychology rejection

,

organ transplantation

,

graft rejection

,

adenocarcinoma of lung

,

,

aplastic anemia

,

,

carcinoid tumor

,

,

chronic hepatitis c

,

lupus nephritis

,

,

colonic neoplasms

,

retinopathy of prematurity

,

polycythemia vera

,

male breast neoplasms

,

,

,

,

hematologic neoplasms

,

neoplasms by histologic type

,

left ventricular dysfunction

,

st elevation myocardial infarction

,

non-st elevated myocardial infarction

,

,

,

,

infectious skin diseases

,

soft tissue infections

,

,

malignant carcinoid syndrome

,

serotonin syndrome

,

erectile dysfunction

,

peanut hypersensitivity

,

allergic rhinitis seasonal

,

,

,

haemophilus infections

,

,

cerebrotendinous xanthomatosis

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

neovascular glaucoma

,

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

chronic obstructive pulmonary disease

,

,

alpha 1-antitrypsin deficiency

,

lymphoproliferative disorders

,

,

breast neoplasms

,

,

macular degeneration

,

,

,

,

kidney transplantation

,

vision disorders

,

choroidal neovascularization

,

type 2 diabetes mellitus

,

neoplasm metastasis

,

retinal vein occlusion

,

chronic urticaria

,

diabetes mellitus

,

liver transplantation

,

essential hypertension

,

multiple sclerosis

,

diabetic retinopathy

,

brain neoplasms

,

relapsing-remitting multiple sclerosis

,

kidney diseases

,

metabolic syndrome

,

renal insufficiency

,

,

pancreatic neoplasms

,

,

chronic kidney failure

,

,

retinal diseases

,

systolic heart failure

,

insulin resistance

,

,

geographic atrophy

,

parkinson disease

,

diastolic heart failure

,

chronic renal insufficiency

,

,

diabetic nephropathies

,

wet macular degeneration

,

,

,

retinal neovascularization

,

polypoidal choroidal vasculopathy

,

liver cirrhosis

,

,

diabetes complications

,

isolated systolic hypertension

,

systolic murmurs

,

,

left ventricular hypertrophy

,

,

glucose intolerance

,

,

chronic progressive multiple sclerosis

,

,

,

membranous glomerulonephritis

,

,

,

pathologic neovascularization

,

tick-borne encephalitis

,

,

,

,

renal replacement therapy

,

,

prehypertension

,

,

staphylococcal skin infections

,

,

,

neurobehavioral manifestations

,

heart transplantation

,

pituitary acth hypersecretion

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

,

pituitary neoplasms

,

,

sexual infantilism

,

heart-lung transplantation

,

,

coronavirus infections

,

,

polyomavirus infections

,

retinal detachment

,

atrial fibrillation

,

iga glomerulonephritis

,

focal segmental glomerulosclerosis

,

nephrosclerosis

,

allergic conjunctivitis

,

reperfusion injury

,

delayed graft function

,

food hypersensitivity

,

islet cell adenoma

,

metabolic bone diseases

,

cryopyrin-associated periodic syndromes

,

,

,

,

immunosuppression therapy

,

angina pectoris

,

microvascular angina

,

spinal muscular atrophies of childhood

,

hematopoietic stem cell transplantation

Globulin, immune

chronic hepatitis b

,

chronic hepatitis

,

,

hepatocellular carcinoma

,

liver neoplasms

Butylscopolamine bromide

cognitive dysfunction

,

alzheimer disease

,

memory disorders

,

,

pharmacokinetics

,

prostatic neoplasms

,

,

pulmonary hypertension

,

breast neoplasms

,

organophosphate poisoning

,

,

blood flow velocity

,

coronary circulation

,

,

,

psychotic disorders

,

,

nerve degeneration

,

,

anesthesia recovery period

,

premature obstetric labor

,

urinary bladder neoplasms

,

,

,

,

therapeutic abortion

,

,

depressive disorder

,

olfaction disorders

,

,

bipolar disorder

,

,

gastrointestinal diseases

,

digestive system diseases

,

,

,

ovarian neoplasms

,

spinal cord injuries

,

space motion sickness

,

promyelocytic leukemia acute

,

,

heart valve diseases

,

,

treatment-resistant schizophrenia

,

amyotrophic lateral sclerosis

,

,

myeloid leukemia acute

,

,

,

,

,

,

chronic kidney failure

,

,

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

endometrial neoplasms

,

,

obstetrical analgesia

,

,

,

cystic fibrosis

,

congenital heart defects

,

,

motion sickness

,

altitude sickness

,

,

disease progression

,

,

,

cardiovascular diseases

,

critical illness

,

premature birth

,

colorectal neoplasms

,

obstetric labor

,

rectal neoplasms

,

,

neuroendocrine tumors

,

,

,

,

,

respiratory tract diseases

,

respiration disorders

,

,

gastrointestinal endoscopy

,

intestinal diseases

,

pancreatic diseases

,

endoscopic retrograde cholangiopancreatography

,

bile duct diseases

,

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

,

healthy volunteers/patients

,

respiratory aspiration

,

,

,

postoperative nausea and vomiting

,

,

,

acute kidney injury

,

post-dural puncture headache

,

postoperative pain

,

major depressive disorder

,

,

,

pseudopseudohypoparathyroidism

,

pseudohypoparathyroidism

,

,

kidney diseases

,

non-small-cell lung carcinoma

,

chronic disease

,

,

,

pulmonary emphysema

,

,

,

wounds and injuries

,

,

obstetric labor complications

,

bariatric surgery

,

,

allergic rhinitis

,

,

chronic bronchitis

,

,

drug-related side effects and adverse reactions

,

,

,

gastroenteritis

,

,

myocardial infarction

,

,

renal insufficiency

,

obstetric delivery

,

first labor stage

,

,

,

respiratory sounds

,

,

airway obstruction

,

nephrolithiasis

,

,

,

,

coronary artery disease

,

chronic renal insufficiency

,

bronchiolitis obliterans

,

bronchiolitis obliterans syndrome

,

,

personal satisfaction

,

adenomatous polyps

,

respiratory tract infections

,

,

,

hypersensitivity

,

tick-borne encephalitis

,

,

abdominal aortic aneurysm

,

,

immunomodulation

,

aortic aneurysm

,

vascular surgical procedures

,

elective surgical procedures

,

,

,

inferior wall myocardial infarction

,

,

,

systemic inflammatory response syndrome

,

,

,

,

systemic scleroderma

,

diffuse scleroderma

,

,

,

headache disorders

,

central nervous system diseases

,

nervous system diseases

,

,

bronchial hyperreactivity

,

choledocholithiasis

,

,

fallopian tube diseases

,

,

,

,

bronchoconstriction

,

,

aids dementia complex

,

premature aging

,

airway remodeling

,

intracytoplasmic sperm injections

,

,

magnetic resonance imaging

,

peritoneal neoplasms

,

irritable bowel syndrome

,

,

ulcerative colitis

,

colonic pouches

,

esophageal and gastric varices

,

ovarian epithelial carcinoma

,

neurotoxicity syndromes

,

,

,

conduction anesthesia

,

intravenous anesthesia

,

female genital neoplasms

,

atrial fibrillation

,

,

angle-closure glaucoma

,

postoperative period

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